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MLB • September 23, 2026

Cardinals flip Pirates’ early edge with five-run third and fourth in 5-1 win

A game that began with one emphatic Pirates swing ended as a lesson in sustained reply, with the St. Louis Cardinals turning Brandon Lowe’s early home run into a 5-1 victory over Pittsburgh at PNC Park by taking control of the third and fourth innings.

MLB / FINAL
St. Louis Cardinals5 — 1Pittsburgh Pirates
St. Louis CardinalsPittsburgh Pirates

Lowe’s homer started it; the Cardinals changed the script

For two innings, Pittsburgh had the game exactly where it wanted it. Lowe’s 434-foot drive to right-center in the second inning gave the Pirates a 1-0 lead and briefly supplied the cleanest offensive moment of the night for the home side.

What followed was the decisive turn. St. Louis did not answer with one overwhelming swing, but with a string of connected plays in the third. Alec Burleson singled to center to bring home JJ Wetherholt and tie the game, while Ivan Herrera advanced to third. Moments later, Herrera scored on a wild pitch by Curtis, pushing the Cardinals in front. Leo Bernal then added another single, this one to right, and Burleson came home for a 3-1 lead.

That inning mattered because it erased Pittsburgh’s advantage and changed the game from a one-swing contest into a chase. The Cardinals made sure it did not stop there. In the fourth, Masyn Winn doubled to center to score José Fermín, and Wetherholt followed with a single to right that brought Winn home. By the end of the fourth, St. Louis had built all the cushion it would need at 5-1.

A middle-order answer without the one big blast

There is something telling about the way St. Louis built this win. The Cardinals finished with 10 hits, outpacing Pittsburgh’s six, and their scoring came from steady accumulation rather than one dramatic blow. Burleson tied the game and later scored. Wetherholt scored the first Cardinals run and drove in the fifth. Herrera’s trip around the bases turned into the go-ahead run, and Bernal, Winn and Fermín all had direct roles in the rally that separated the clubs.

That is often the shape of a solid road win: an early deficit absorbed, pressure reapplied, then broadened. The scoring summary shows St. Louis getting runs from a single, a wild pitch, another single, a double and one more single. Five runs, five different moments, and each one pushed the Pirates a little farther away from their opening lead.

Pittsburgh’s problem was not sloppiness in the field; neither team committed an error. It was the inability to answer once the Cardinals seized the middle innings. Lowe’s home run remains the Pirates’ standout detail from the scoreboard, but after that second-inning shot, the offense could not find the next run. Six hits can be enough to keep a game tight, yet the Pirates were held to one on a night when St. Louis kept adding pressure.

Our take: the game swung when one inning became two

Our take: the third inning was the pivot, but the fourth made the result feel settled. Teams recover from a 3-1 deficit all the time; they recover less often when the opponent immediately follows with two more runs. That is what gives this Cardinals win some substance beyond the final margin. They did not merely erase an early problem. They answered it, then reinforced the answer before Pittsburgh could reset.

For St. Louis, the encouraging part is obvious. Falling behind 1-0 did not change the night’s direction for long, and the offense showed enough variety to score without waiting for a home run. If there is a reasonable area to sharpen, it is simply this: a 10-hit game can sometimes create even more separation than four runs of margin. That is not a complaint so much as a reminder that a productive night still left room for more.

For Pittsburgh, the clearest lesson is about containment. A one-run lead turned into a two-run deficit in the third and a four-run deficit by the end of the fourth. When games tilt that quickly, the immediate task is stopping the inning from growing, then finding a reply before the scoreboard hardens. The Pirates never found that reply here. The final line says 5-1, but the real story is narrower and sharper: St. Louis owned two innings, and those two innings owned the game.

Scoring moments

  1. 2nd Inning

    Lowe homered to right center (434 feet).

  2. 3rd Inning

    Burleson singled to center, Wetherholt scored, Herrera to third.

  3. 3rd Inning

    Herrera scored on Curtis wild pitch, Burleson to second on wild pitch by Curtis.

  4. 3rd Inning

    Herrera scored on Curtis wild pitch, Burleson to second on wild pitch by Curtis.

  5. 3rd Inning

    Bernal singled to right, Burleson scored.

  6. 4th Inning

    Winn doubled to center, Fermín scored.

  7. 4th Inning

    Wetherholt singled to right, Winn scored.

St. Louis Cardinals — Batting
PlayerH-ABABRHRBIHRBBK#PAVGOBPSLG
JJ Wetherholt0-000000106.240.340.365
Ivan Herrera0-110000003.245.356.384
Alec Burleson0-110000015.279.345.462
Jordan Walker0-110000004.272.330.470
Leo Bernal0-110000016.295.337.487
Nolan Gorman1-110100004.189.273.317
Jose Fermin0-110000002.250.313.361
Nathan Church0-110000004.252.297.374
Masyn Winn0-000000000.234.309.319
St. Louis Cardinals — Pitching
PlayerIPHRERBBKHRPC-STERAPC
Matthew Liberatore1.000000011-55.3311
Pittsburgh Pirates — Batting
PlayerH-ABABRHRBIHRBBK#PAVGOBPSLG
Konnor Griffin0-110000002.270.323.396
Rafael Flores Jr.0-110000005.277.349.540
Bryan Reynolds0-110000004.262.364.424
Brandon Lowe0-000000000.260.330.489
Nick Gonzales0-000000000.302.365.389
Ronny Simon0-000000000.294.333.412
Ryan O'Hearn0-000000000.264.330.441
Jared Triolo0-000000000.240.311.306
Jake Mangum0-000000000.279.336.370
Pittsburgh Pirates — Pitching
PlayerIPHRERBBKHRPC-STERAPC
Lake Bachar1.210012030-183.4930
Brandon Eisert0.10000004-25.064
St. Louis Cardinals — Team statistics
Batting · Games Played1
Batting · Team Games Played1
Batting · Hit By Pitch0
Batting · Ground Balls0
Batting · Strikeouts2
Batting · Runs Batted In0
Batting · Sacrifice Hit0
Batting · Hits1
Batting · Stolen Bases0
Batting · Walks1
Batting · Catcher Interference0
Batting · Runs0
Batting · Ground Into Double Play0
Batting · Sacrifice Flies0
Batting · At Bats7
Batting · Home Runs0
Batting · Grand Slam Home Runs0
Batting · Runners Left On Base5
Batting · Triples0
Batting · Game Winning RBIs0
Batting · Intentional Walks0
Batting · Doubles0
Batting · Fly Balls0
Batting · Caught Stealing0
Batting · Pitches34
Batting · Games Started0
Batting · Pinch At Bats0
Batting · Pinch Hits0
Batting · Player Rating0.0
Batting · Is Qualified1
Batting · Is Qualified In Steals0
Batting · Total Bases1
Batting · Plate Appearances8
Batting · Projected Home Runs0.0
Batting · Extra Base Hits0
Batting · Runs Created0.2
Batting · Batting Average.143
Batting · Pinch Hit Average.000
Batting · Slugging Percentage.143
Batting · Secondary Average.143
Batting · On Base Percentage.250
Batting · OBP Pct + SLG Pct.393
Batting · Ground To Fly Ball Ratio0.0
Batting · Runs Created Per 27 Outs1.0
Batting · Batter Rating1.0
Batting · At Bats Per Home Run0.0
Batting · Stolen Base Percentage0.00
Batting · Pitches Per Plate Appearance4.25
Batting · Isolated Power.000
Batting · Walk To Strikeout Ratio0.50
Batting · Walks Per Plate Appearance.125
Batting · Secondary Average Minus Batting Average.000
Batting · Runs Produced0.0
Batting · Runs Ratio0.0
Batting · Patience Ratio0.2
Batting · Balls In Play Average0.2
Batting · MLB Rating59.3
Batting · Offensive Wins Above Replacement0.0
Batting · Wins Above Replacement0.0
Pitching · Games Played1
Pitching · Team Games Played1
Pitching · Saves0
Pitching · Ground Balls0
Pitching · Strikeouts0
Pitching · Sacrifice Flies0
Pitching · Losses0
Pitching · Hits0
Pitching · Earned runs0
Pitching · Batters Hit0
Pitching · Walks0
Pitching · Runs0
Pitching · Stolen Bases0
Pitching · Caught Stealing0
Pitching · Sacrifice Bunts0
Pitching · Save Opportunities0
Pitching · Home Runs0
Pitching · Triples0
Pitching · Finishes0
Pitching · Balks0
Pitching · Intentional Walks0
Pitching · Fly Balls3
Pitching · Batters Faced3
Pitching · Holds0
Pitching · Doubles0
Pitching · Wins0
Pitching · Complete Games0
Pitching · Perfect Games0
Pitching · Wild Pitches0
Pitching · Runs Batted In0
Pitching · Third Innings Pitched3
Pitching · Earned Runs0
Pitching · Shutouts0
Pitching · Pickoff Attempts0
Pitching · Pitches11
Pitching · Run Support0.0
Pitching · Catcher Interference0
Pitching · Pitches As Starter0
Pitching · Games Started1
Pitching · Game Score0.0
Pitching · Quality Starts0
Pitching · Inherited Runners0
Pitching · Inherited Runners Scored0
Pitching · Player Rating0.0
Pitching · At Bats3
Pitching · Total Bases0
Pitching · Is Qualified1
Pitching · Is Qualified0
Pitching · Full Innings1
Pitching · Partial Innings0
Pitching · Blown Saves0
Pitching · Innings pitched1.0
Pitching · Earned Run Average0.00
Pitching · Walks Plus Hits Per Inning Pitched0.00
Pitching · Win Percentage.000
Pitching · Caught Stealing Percentage0.0
Pitching · Ground To Fly Ball Ratio0.0
Pitching · Pitches Per Start0.0
Pitching · Pitches Per Inning11.0
Pitching · Pitches Per Plate Appearance3.7
Pitching · Run Support Average0.0
Pitching · Opponent Batting Average.000
Pitching · Opponent's Slugging pct..000
Pitching · Opponent's On-base pct..000
Pitching · Opponent's OPB Pct + SLG Pct.000
Pitching · Save Percentage0.0
Pitching · Strikeouts Per 9 Innings0.0
Pitching · Strikeout To Walk Ratio0.0
Pitching · Tough Losses0
Pitching · Cheap Wins0
Pitching · Save Opportunities Per Win0.0
Pitching · Balls In Play Average0.000
Pitching · Total Bases0.000
Pitching · Pitch Count0
Pitching · Strikes5
Pitching · Strike To Pitch Ratio0.0
Pitching · Wins Above Replacement0.0
Fielding · Games Played1
Fielding · Team Games Played1
Fielding · Double Plays0
Fielding · Opportunities0
Fielding · Errors0
Fielding · Passed Balls0
Fielding · Assists0
Fielding · Outfield Assists0
Fielding · Pickoffs0
Fielding · Putouts3
Fielding · Outs On Field0
Fielding · TP0
Fielding · Balls In Zone0
Fielding · Extra Bases0
Fielding · Outs Made0
Fielding · Hits0
Fielding · Total Bases0
Fielding · Games Started0
Fielding · Third Innings Played0.0
Fielding · Caught Stealing0
Fielding · Stolen Bases Allowed0
Fielding · Earned Runs0
Fielding · Qualified1
Fielding · Qualified Catcher1
Fielding · Qualified Pitcher0
Fielding · Successful Chances0
Fielding · Total Chances0
Fielding · Full Innings0
Fielding · Part Innings Played0
Fielding · Fielding Percentage0.000
Fielding · Range Factor0.0
Fielding · Zone Rating0.0
Fielding · Caught Stealing Percentage0.000
Fielding · Earned Run Average0.0
Fielding · Defensive Wins Above Replacement0.0
Pittsburgh Pirates — Team statistics
Batting · Games Played1
Batting · Team Games Played1
Batting · Hit By Pitch0
Batting · Ground Balls0
Batting · Strikeouts0
Batting · Runs Batted In0
Batting · Sacrifice Hit0
Batting · Hits0
Batting · Stolen Bases0
Batting · Walks0
Batting · Catcher Interference0
Batting · Runs0
Batting · Ground Into Double Play0
Batting · Sacrifice Flies0
Batting · At Bats3
Batting · Home Runs0
Batting · Grand Slam Home Runs0
Batting · Runners Left On Base0
Batting · Triples0
Batting · Game Winning RBIs0
Batting · Intentional Walks0
Batting · Doubles0
Batting · Fly Balls0
Batting · Caught Stealing0
Batting · Pitches11
Batting · Games Started0
Batting · Pinch At Bats0
Batting · Pinch Hits0
Batting · Player Rating0.0
Batting · Is Qualified0
Batting · Is Qualified In Steals0
Batting · Total Bases0
Batting · Plate Appearances3
Batting · Projected Home Runs0.0
Batting · Extra Base Hits0
Batting · Runs Created-0.3
Batting · Batting Average.000
Batting · Pinch Hit Average.000
Batting · Slugging Percentage.000
Batting · Secondary Average.000
Batting · On Base Percentage.000
Batting · OBP Pct + SLG Pct.000
Batting · Ground To Fly Ball Ratio0.0
Batting · Runs Created Per 27 Outs-2.7
Batting · Batter Rating0.0
Batting · At Bats Per Home Run0.0
Batting · Stolen Base Percentage0.00
Batting · Pitches Per Plate Appearance3.67
Batting · Isolated Power.000
Batting · Walk To Strikeout Ratio0.00
Batting · Walks Per Plate Appearance.000
Batting · Secondary Average Minus Batting Average.000
Batting · Runs Produced0.0
Batting · Runs Ratio0.0
Batting · Patience Ratio0.0
Batting · Balls In Play Average0.0
Batting · MLB Rating58.3
Batting · Offensive Wins Above Replacement0.0
Batting · Wins Above Replacement0.0
Pitching · Games Played1
Pitching · Team Games Played1
Pitching · Saves0
Pitching · Ground Balls2
Pitching · Strikeouts2
Pitching · Sacrifice Flies0
Pitching · Losses0
Pitching · Hits1
Pitching · Earned runs0
Pitching · Batters Hit0
Pitching · Walks1
Pitching · Runs0
Pitching · Stolen Bases0
Pitching · Caught Stealing0
Pitching · Sacrifice Bunts0
Pitching · Save Opportunities0
Pitching · Home Runs0
Pitching · Triples0
Pitching · Finishes0
Pitching · Balks0
Pitching · Intentional Walks0
Pitching · Fly Balls2
Pitching · Batters Faced8
Pitching · Holds0
Pitching · Doubles0
Pitching · Wins0
Pitching · Complete Games0
Pitching · Perfect Games0
Pitching · Wild Pitches0
Pitching · Runs Batted In0
Pitching · Third Innings Pitched6
Pitching · Earned Runs0
Pitching · Shutouts0
Pitching · Pickoff Attempts0
Pitching · Pitches34
Pitching · Run Support0.0
Pitching · Catcher Interference0
Pitching · Pitches As Starter0
Pitching · Games Started1
Pitching · Game Score0.0
Pitching · Quality Starts0
Pitching · Inherited Runners0
Pitching · Inherited Runners Scored0
Pitching · Player Rating0.0
Pitching · At Bats7
Pitching · Total Bases1
Pitching · Is Qualified1
Pitching · Is Qualified0
Pitching · Full Innings2
Pitching · Partial Innings0
Pitching · Blown Saves0
Pitching · Innings pitched2.0
Pitching · Earned Run Average0.00
Pitching · Walks Plus Hits Per Inning Pitched1.00
Pitching · Win Percentage.000
Pitching · Caught Stealing Percentage0.0
Pitching · Ground To Fly Ball Ratio1.0
Pitching · Pitches Per Start0.0
Pitching · Pitches Per Inning17.0
Pitching · Pitches Per Plate Appearance4.3
Pitching · Run Support Average0.0
Pitching · Opponent Batting Average.143
Pitching · Opponent's Slugging pct..143
Pitching · Opponent's On-base pct..250
Pitching · Opponent's OPB Pct + SLG Pct.393
Pitching · Save Percentage0.0
Pitching · Strikeouts Per 9 Innings9.0
Pitching · Strikeout To Walk Ratio2.0
Pitching · Tough Losses0
Pitching · Cheap Wins0
Pitching · Save Opportunities Per Win0.0
Pitching · Balls In Play Average0.200
Pitching · Total Bases1.000
Pitching · Pitch Count0
Pitching · Strikes20
Pitching · Strike To Pitch Ratio0.0
Pitching · Wins Above Replacement0.0
Fielding · Games Played1
Fielding · Team Games Played1
Fielding · Double Plays0
Fielding · Opportunities0
Fielding · Errors0
Fielding · Passed Balls0
Fielding · Assists2
Fielding · Outfield Assists0
Fielding · Pickoffs0
Fielding · Putouts6
Fielding · Outs On Field0
Fielding · TP0
Fielding · Balls In Zone0
Fielding · Extra Bases0
Fielding · Outs Made0
Fielding · Hits0
Fielding · Total Bases0
Fielding · Games Started0
Fielding · Third Innings Played0.0
Fielding · Caught Stealing0
Fielding · Stolen Bases Allowed0
Fielding · Earned Runs0
Fielding · Qualified1
Fielding · Qualified Catcher1
Fielding · Qualified Pitcher0
Fielding · Successful Chances0
Fielding · Total Chances0
Fielding · Full Innings0
Fielding · Part Innings Played0
Fielding · Fielding Percentage0.000
Fielding · Range Factor0.0
Fielding · Zone Rating0.0
Fielding · Caught Stealing Percentage0.000
Fielding · Earned Run Average0.0
Fielding · Defensive Wins Above Replacement0.0